Resumo Este artigo, segmento do trabalho de doutorado do autor, apresenta uma revisão integrativa de literatura nas diversas áreas de conhecimento que abordam a temática adolescência e ato infracional. Segue o método sistemático e o formato narrativo, tomando a ciência como prática social e levantando aspectos qualitativos da literatura produzida entre 2011 e 2020, com enfoque no estado atual do conhecimento e no modo como se tem produzido os saberes científicos nesse campo. Os resultados apresentam recortes importantes acerca da problemática, porém, de modo geral, o panorama revela saberes fragmentados, com discursos disciplinares e pouco dialogados. Os modos de considerar o adolescente nas pesquisas tendem a se dar com práticas de silenciamento, priorizando o saber-fazer-poder-dizer de adultos, “especialistas” e instituições. Ressalta-se a importância do pensamento crítico, decolonial, complexo e transdisciplinar como orientadores de uma ciência capaz de integrar diferentes saberes, rompendo com lógicas estanques de separação, oposição, redução, hierarquização e silenciamento.

Abstract This article, segment of the author's doctoral work, presents an integrative literature review in the different areas of knowledge that address the issue of adolescence and infractions. It follows the systematic method and narrative format, taking science as a social practice and raising qualitative aspects of the literature produced between 2011 and 2020, focusing on the current state of knowledge and the way scientific knowledge in this field has been produced. The results show important insights into this issue, however, in general, the panorama reveals fragmented knowledge, with disciplinary scientific discourses and little dialogue. The ways of considering adolescents in research tend to be based on silencing practices, prioritizing know-can-do-say from adults, “experts” and institutions. The importance of critical, decolonial, complex and transdisciplinary thinking is highlighted as guiding a science capable of integrating different knowledge, breaking with stagnant logics of separation, opposition, reduction, hierarchization and silencing.

Abstract This article, segment of the author's doctoral work, presents an integrative literature review in the different areas of knowledge that address the issue of adolescence and infractions. It follows the systematic method and narrative format, taking science as a social practice and raising qualitative aspects of the literature produced between 2011 and 2020, focusing on the current state of knowledge and the way scientific knowledge in this field has been produced. The results show important insights into this issue, however, in general, the panorama reveals fragmented knowledge, with disciplinary scientific discourses and little dialogue. The ways of considering adolescents in research tend to be based on silencing practices, prioritizing know-can-do-say from adults, “experts” and institutions. The importance of critical, decolonial, complex and transdisciplinary thinking is highlighted as guiding a science capable of integrating different knowledge, breaking with stagnant logics of separation, opposition, reduction, hierarchization and silencing.

Resumo Este artigo, segmento do trabalho de doutorado do autor, apresenta uma revisão integrativa de literatura nas diversas áreas de conhecimento que abordam a temática adolescência e ato infracional. Segue o método sistemático e o formato narrativo, tomando a ciência como prática social e levantando aspectos qualitativos da literatura produzida entre 2011 e 2020, com enfoque no estado atual do conhecimento e no modo como se tem produzido os saberes científicos nesse campo. Os resultados apresentam recortes importantes acerca da problemática, porém, de modo geral, o panorama revela saberes fragmentados, com discursos disciplinares e pouco dialogados. Os modos de considerar o adolescente nas pesquisas tendem a se dar com práticas de silenciamento, priorizando o saber-fazer-poder-dizer de adultos, “especialistas” e instituições. Ressalta-se a importância do pensamento crítico, decolonial, complexo e transdisciplinar como orientadores de uma ciência capaz de integrar diferentes saberes, rompendo com lógicas estanques de separação, oposição, redução, hierarquização e silenciamento.

Abstract Introduction Coronary artery bypass grafting (CABG) surgery is associated with a decline in ventilatory muscle strength and lung function. Inspiratory muscle training (IMT) based on anaerobic threshold (AT) has been used to minimize the impact of CABG on these parameters, but the long-term impact is unknown. Objective To test the hypothesis that AT-based IMT improves inspiratory muscle strength and lung function even six months after CABG. Methods This is a randomized controlled clinical trial. In the preoperative period, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), vital capacity (VC) and peak expiratory flow (PEF) rate were assessed. On the first postoperative day, patients were randomized into two groups: AT-based IMT (IMT-AT) (n=21) where the load was prescribed based on glycemic threshold and conventional IMT (IMT-C) (n=21), with load of 40% of MIP. Patients were trained during hospitalization until the day of discharge and were assessed at discharge and six months later. For within-group comparison, paired Student's t-test or Wilcoxon test was used, and independent Student's t-test or the Mann-Whitney test was used to analyze the different time points. A p<0.05 was considered significant. Results At six months after CABG surgery, statistical difference was found between the IMT-AT and the IMT-C groups in MIP (difference between the means of -5cmH2; 95% CI=- 8.21to-1.79) and VC (difference between the means of -2ml/kg;95%CI=-3.87to-0.13). No difference was found between groups in the other variables analyzed. Conclusion IMT-AT promoted greater recovery of inspiratory muscle strength and VC after six months of CABG when compared to conventional training.

Abstract Aiming to understand the multiple versions of reality produced in the daily practices of a child’s relational network to which externalizing behavior problems refer, in the field of mental health, this article reports a case study, carried out in 2017, based on the approaches of the Actor-Network and Discursive Practices and Production of Meanings in Everyday Life. The empirical referent of the research is a boy with a diagnostic hypothesis of ADHD and ODD, articulated with human and non-human actants in different dimensions of their relationships. The results expose everyday interactions, crossed by intergenerational conflicts, producing heterogeneous realities and meanings, in the transit between apparently antagonistic ideas (angelic-diabolical/child-adult). Children, with ir different behaviors, just like adults, acts and are acted upon in power relations, in a fluid co-production of conflicts and understandings that express always uncertain and localized versions of what would be “the child with externalizing behaviors”.

Resumen Con el objetivo de comprender las múltiples versiones de la realidad que se producen en las prácticas cotidianas de la red relacional de un niño a la que se refieren los problemas de comportamiento externalizante, en el campo de la salud mental, este artículo relata un estudio de caso, realizado en 2017, a partir de los enfoques de la Teoría Actor-Red y Prácticas Discursivas y Producción de Sentidos en la Vida Cotidiana. El referente empírico de la investigación es un niño con hipótesis diagnóstica de TDAH y TND, articulado con actantes humanos y no humanos en diferentes dimensiones de sus relaciones. Los resultados exponen las interacciones cotidianas, atravesadas por conflictos intergeneracionales, produciendo realidades y significados heterogéneos, en el tránsito entre ideas aparentemente antagónicas (angelical-diabólica/niño-adulto). Los niños, con sus diferentes conductas, al igual que los adultos, actúan y son actuados en relaciones de poder, en una fluida coproducción de conflictos y entendimientos que expresan versiones siempre inciertas y localizadas de lo que sería “el niño con conductas externalizantes”.

Resumo Visando compreender as múltiplas versões de realidade produzidas nas práticas cotidianas da rede relacional de uma criança à qual se referem problemas de comportamentos externalizantes, no campo da saúde mental, este artigo relata um estudo de caso, realizado em 2017, a partir das abordagens da Teoria Ator-Rede e das Práticas Discursivas e Produção de Sentidos no Cotidiano. O referente empírico da pesquisa é um menino com hipótese diagnóstica de TDAH e TOD, articulado com actantes humanos e não humanos em dimensões diversas de suas relações. Os resultados expõem as interatuações cotidianas, atravessadas por conflitos intergeracionais, produzindo realidades e sentidos heterogêneos, no trânsito entre ideias aparentemente antagônicas (angelical-diabólico/criança-adulto). A criança, com seus comportamentos diversos, tal qual os adultos, atua e é atuada em relações de poder, numa coprodução fluida de conflitos e entendimentos que expressam versões sempre incertas e localizadas do que seria “a criança com comportamentos externalizantes”.

ABSTRACT Introduction: We analyzed voting patterns in municipalities in the 2014 and 2018 elections for Federal Deputy, comparing our findings against previous studies on the 1994 and 1998 elections. Our objective was to identify similarities or changes in voter behavior over this period. Materials and methods: The research is based on a quantitative and a comparative approach. From information available on the Superior Electoral Court's (TSE) archive, we built a database to carry out SQL and regression queries. We also used the “R” software to calculate the relevant comparable magnitudes. Results: Compared to twenty years ago, the differences between two consecutive elections have become more pronounced. In the 2014 and 2018 elections, the variation of the national average of effective candidates per municipality showed higher and unstable values. In 2018 we find a preponderance of municipalities with fragmented voting pattern. In the 100 largest Brazilian municipalities, there are hardly any examples of concentrated voting in the 2014 and 2018 elections. The Northeast continues to be the region with the most concentrated voting pattern, while the South has the most dispersed voting pattern. Discussion: Notably, the most populated municipalities revealed to be more electorally competitive. Although we cannot extrapolate our findings to infer future results, our work is relevant insofar as it provides more recent data on the voting profile in Brazilian municipalities, which may contribute both to understand changes in the political scenario as well as to subsidize decisions in several related areas, such as the Brazilian electoral system.

RESUMO Introdução: Analisamos os padrões de votação nos municípios nos pleitos de 2014 e 2018 para o cargo de Deputado Federal, comparando os resultados com aqueles encontrados em estudos prévios sobre as eleições de 1994 e 1998. Nosso objetivo é verificar similaridades ou alterações no comportamento dos eleitores nesse intervalo de tempo. Materiais e métodos: A pesquisa é quantitativa e comparativa. São processadas regressões e consultas SQL em base de dados construída pelos autores a partir das informações disponíveis no acervo do Tribunal Superior Eleitoral. Também se utiliza software “R” para calcular as grandezas relevantes a serem comparadas. Resultados: Ocorreram mudanças em relação há vinte anos e as diferenças existentes entre dois pleitos consecutivos ficaram mais acentuadas. A variação da média nacional do número efetivo de candidatos por município revelou valores mais altos e instáveis entre os pleitos de 2014 e 2018. Em 2018 houve preponderância de municípios com votação fragmentada. Nos 100 maiores municípios brasileiros, quase não houve casos de votação concentrada nos pleitos de 2014 e 2018. O Nordeste permanece a região com a votação mais concentrada e o Sul com a votação mais dispersa. Discussão: Notadamente os maiores municípios se mostraram mais competitivos eleitoralmente. Ainda que os resultados obtidos não possam ser extrapolados para inferir resultados futuros, o trabalho se mostra relevante por oferecer dados mais recentes sobre o perfil de votação nos municípios brasileiros, podendo contribuir tanto para a compreensão de mudanças no cenário político, como também para subsidiar decisões em diversas áreas relacionadas, como por exemplo o sistema eleitoral brasileiro.

Abstract This research identifies in job postings the requirements for data scientists in Brazil. To analyze these documents, it adopts text mining methods of analysis: n-gram, topic modeling, and clustering. The findings point to a concentration of job opportunities in São Paulo while demonstrating that the remote modality is the second most offered. Additionally, it highlights that salaries in Brazil are below the average of other countries, even if organizations look for experienced professionals with an elevated level of education. About the requirements, there is a predominance of technical skills such as machine learning, statistical models, python, and database, among others. The results also demonstrate that n-gram and clustering are more suitable for text mining techniques than topic modeling.

Resumo Esta pesquisa identifica os requisitos para cientistas de dados no Brasil em anúncios de emprego. Para analisar estes documentos, adota métodos de mineração de texto: n-grama, modelagem de tópico e agrupamento. Os resultados apontam uma concentração de vagas em São Paulo e revelam que a modalidade remota é a segunda mais ofertada. Além disso, destaca que os salários no Brasil estão abaixo da média de outros países, mesmo que as organizações procurem por profissionais experientes e com alto nível educacional. Quanto aos requisitos, há o predomínio de habilidades técnicas como machine learning, modelos estatísticos, python, banco de dados, dentre outras. Para as técnicas de mineração, demonstra que n-grama e o agrupamento são mais adequadas que a modelagem de tópicos.

Abstract Introduction: Coronary artery bypass grafting (CABG) is a procedure associated with a decline in pulmonary function. Among the main causes is the presence of the drain that is usually positioned in the intercostal or subxiphoid region. Objective: To measure the interference of drains positioning on pulmonary function in patients undergoing CABG. Methods: Observational study that assessed preoperative pulmonary function through vital capacity (VC), maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and peak expiratory flow (PEF). These variables were evaluated in three different moments: in the presence of two drains, when removing one, and after removing all drains. Results: We evaluated 45 patients with a mean age of 62 ± 7 years with male prevalence of 29 (64%) individuals. The insertion of drains caused a decline in pulmonary function after surgery by reducing MIP by 48%, MEP by 11%, VC by 39%, and PEF by 6%. Conclusion: This study has demonstrated that drains positioning after CABG surgery may produce weakness of the respiratory muscles, change ventilatory mechanics, and impair normal pulmonary function postoperatively.

Abstract The growth, sexual maturity and fertility-related parameters related of young Nellore bulls with divergent residual feed intake (RFI) raised on pasture were evaluated. After classification of 48 young males as low and high RFI (more and less efficient, respectively), the animals were evaluated for growth and reproductive parameters at 28-day intervals from 14.3 to 24.6 months of age. The semen was cryopreserved in the last sampling and fresh and post-thaw semen samples were evaluated. Low RFI bulls exhibited higher initial and final body weight (P < 0.05), but feed intake, body condition score and growth measures evaluated by carcass ultrasound were unaffected by RFI (P > 0.05). The scrotal circumference, sperm concentration, defects, and quality of fresh semen, and ultrasonographic testicular characteristics were unaffected by RFI (P > 0.05). However, velocity parameters such as average path and curvilinear velocities determined by computer-assisted sperm analysis of thawed semen submitted to the rapid thermoresistance test were improved (P < 0.05) in low RFI bulls, but this improvement in quality did not enhance in vitro sperm fertilizing ability. Our results demonstrated significant differences in metabolism and growth performance between bulls of divergent RFI. In addition, there was slight improvement in the semen quality of bulls with low RFI bulls, but this did not enhance in vitro fertilizing ability. Selection of beef bulls for RFI can be performed, which will result in economic benefits by improving the growth performance of the animals without affecting reproductive parameters.

RESUMO A institucionalização tem sido associada ao isolamento social, a alterações psicológicas e cognitivas e à diminuição dos níveis de atividade física em idosos. Objetivos: Estimar a prevalência de demência, declínio cognitivo leve (DCL) e dependência funcional em idosos residentes em duas instituições de longa permanência (ILPI) brasileiras. Métodos: Estudo transversal com 185 idosos de ambos os sexos, com 60 anos ou mais, residentes em duas ILPI. O diagnóstico de DCL e demência foi realizado por meio do Manual Diagnóstico e Estatístico de Transtornos Mentais. Resultados: As taxas de prevalência de demência, DCL e dependência funcional em participantes idosos institucionalizados foram 62,3, 15,1 e 78,9%, respectivamente. Houve redução significativa dos escores do miniexame do estado mental de acordo com o aumento do período de institucionalização nas ILPI e a idade dos idosos (p<0,001). Conclusões: A prevalência de demência e dependência funcional de idosos residentes em ILPI foi mais elevada em comparação com outras populações idosas em todo o mundo. Um período maior de institucionalização está relacionado a maior declínio cognitivo.

ABSTRACT Institutionalization has been associated with social isolation, psychological and cognitive changes, and decreased levels of physical activity in older adults. Objectives: The aim of this study was to estimate the prevalence of dementia, mild cognitive impairment (MCI), and functional dependence in older adults dwelling in two different Brazilian long-term care facilities (LTCFs). Methods: This is a cross-sectional study with 185 older people of both sexes, aged 60 years or over, residing in two LTCFs in the city of Montes Claros-MG, Brazil. The diagnosis of MCI and dementia was performed using the Diagnostic and Statistical Manual of Mental Disorders. Results: Prevalence rates of dementia, MCI, and functional dependence in institutionalized older participants were 62.3, 15.1, and 78.9%, respectively. There was a significant reduction of the Mini-Mental State Examination scores according to the increase of the institutionalization period in LCTFs and the age of older adults (p<0.001). Conclusions: Prevalence of dementia and functional dependence of older adults residing in LTCFs exhibited higher rates compared to the other older population worldwide. A higher institutionalization period is related to a greater cognitive decline.

Abstract Background The European Heart Surgery Risk Assessment System (EuroSCORE) and InsCor have been used to predict complications of cardiac surgery. However, their application to predict lung function and functionality is still uncertain. Objective To correlate surgical risk scales with functional independence and pulmonary function in patients undergoing coronary artery bypass grafting. Methods This was a prospective cohort study. In the preoperative period, the two surgical scales were applied, the maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and peak expiratory flow (PEF) were measured, and functionality was assessed using the functional independence measure (FIM). On the seventh postoperative day, the pulmonary function and functionality variables were reevaluated, compared with the preoperative values (delta) and correlated with the risk scales. Correlations of pulmonary function, functional independence and muscle strength variables with the surgical scales were made by Pearson correlation test. The significance level adopted was 5%. Results Thirty-one patients were studied; most were male (77%), with a mean age of 56±8 years. Mean EuroSCORE was 2.3±0.5 and mean InsCOR was 1.2±0.5. MIP, MEP, and PEF reduced 30% (p<0.001), 33% (p<0.001) and 10% (p=0.23), respectively. The EuroSCORE correlated with MIP (r-0.78; p = 0.02) and FIM (r-0.79; p <0.01), and the InsCor correlated with MIP (r-0.77), MEP (r-0.73) and MIF (r-0.89; p=0.02). Conclusion The EuroSCORE showed a strong negative correlation with MIP and FIM, while InsCor had a strong negative correlation with MIP, MEP and FIM. (Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0)

Resumo Os comportamentos externalizantes dizem de um conjunto de reações impulsivas que, exteriorizadas por crianças (ou adolescentes), produzem conflitos e, em padrão repetitivo e persistente, são associados a síndromes psicopatológicas e transtornos. Este artigo tem o objetivo de revisão de literatura sobre o tema, nos três eixos disciplinares da Saúde Coletiva. Segue o método de revisão sistemática, com enfoque empírico e formato narrativo, tomando a ciência como prática social e levantando aspectos qualitativos de literatura produzida entre 2009 e 2019. Os conhecimentos produzidos trazem recortes importantes sobre o tema, porém, o panorama alcançado revela um distanciamento discursivo entre os eixos da epidemiologia e das ciências sociais em saúde, aproximados precariamente no eixo da política, planejamento e gestão em saúde. Os modos de considerar a criança nas pesquisas se dão com o silenciamento infantil, priorizando percepções dos adultos sobre as crianças. Chega-se a considerações sobre a importância de uma efetiva interdisciplinaridade e de uma pedagogia da transdisciplinaridade capaz de transcender o lugar das especialidades e de reconhecer a criança, com a valorização das suas práticas e saberes, como ator central do conhecimento acerca de si mesma.

Abstract The externalizing behaviors refer to a set of impulsive reactions that exteriorized by children (or adolescents) produce conflicts and, in a repetitive and persistent pattern, are associated with psychopathological syndromes and disorders. This article has the objective of empirical review on the subject, in three disciplinary axes of Public Health. It follows the systematic review method, with an empirical focus and narrative format, taking science as social practice and raising qualitative aspects of literature produced between 2009 and 2019. The knowledge produced brings important cuts on the subject, however, the panorama reached reveals a discursive distance between the axes of epidemiology and of the social science, precariously approximated in the axis of health planning. The ways of considering the child in the research are with child silencing, prioritizing adults' perceptions about children. We come to considerations about the importance of effective interdisciplinarity and a pedagogy of transdisciplinarity capable of transcending the place of specialties and of recognizing the child, with the appreciation of his practices and knowledge, as the central actor of knowledge about himself.

RESUMO A problemática da durabilidade de estruturas de concreto armado inseridas em ambientes de severa agressividade se apresenta como uma das principais dificuldades enfrentadas pela cadeia da construção civil. Dos vários agentes capazes de degradar estas estruturas tem-se atenção especial aos íons cloreto capazes de causar a corrosão de armaduras, estes íons estão amplamente presentes em ambientes marinhos. Neste espectro, a estimativa de vida útil das estruturas de concreto armado se torna uma temática fundamental na avaliação da durabilidade de estruturas. Apesar de vários processos causarem penetração de cloretos no concreto tem-se praticamente como consenso que o mecanismo de difusão é o predominante, tendo-se como um modelo clássico de caracterização da penetração de cloretos a 2ª Lei da difusão de Fick. O processo de difusão iônica sofre forte influência do grau de saturação (GS) dos poros do concreto, está influencia incide diretamente sobre o coeficiente de difusão de cloretos (D). Ainda que se tenham desenvolvido metodologias de medição do GS elas se apresentam dispendiosas em tempo e recursos. Objetiva-se então apresentar estimativas do Grau de Saturação, baseadas nas condições ambientais de exposição da estrutura, e analisar a influência deste parâmetro na estimativa de vida útil de elementos estruturais de concreto armado sob a ótica da confiabilidade. São utilizados dados meteorológicos e de medição do GS de duas regiões litorâneas, sendo uma em Rio Grande, no sul do Brasil e outra em Santa Pola, sudeste da Espanha. Obtiveram-se modelos de estimativa do GS do concreto para cada situação pesquisada e também para ambos os ambientes em conjunto. Constatou-se então, através de uma abordagem probabilística, a forte influência do uso destes modelos na estimativa de vida útil de elementos de concreto armado.

ABSTRACT The problematic of the durability of reinforced concrete structures inserted in environments of severe aggressiveness is presented as one of the main difficulties faced by the civil construction chain. Of the various agents capable of degrading these structures, special attention is paid to chloride ions capable of causing corrosion of reinforcing steel, these ions are widely present in marine environments. In this sense, the estimated useful service life of reinforced concrete structures becomes a fundamental theme in the evaluation of the durability of concrete structures. Although several processes cause penetration of chlorides in the concrete, it is practically agreed that the diffusion mechanism is the predominant one, being Fick’s 2nd Law of diffusion a classic model for the characterization of chloride penetration into concrete. The ionic diffusion process is strongly influenced by the saturation degree (GS) of the pores in the concrete, it influences directly on the chloride diffusion coefficient (D). Although GS measurement methodologies have been developed, they are costly in time and resources. The objective of this study is to present estimates of GS, based on the environmental exposure conditions of the structure, and to analyze the influence of this parameter on the estimated useful service life of structural elements of reinforced concrete from the point of view of reliability. Meteorological and GS measurement data from two coastal regions are used, one in Rio Grande, in southern Brazil and the other in Santa Pola, southeast of Spain. Concrete GS estimation models were obtained for each studied situation and also for both environments together. It was verified, through a probabilistic approach, the strong influence of the use of these models in the estimation of useful service life of reinforced concrete structures.

Resumo Os comportamentos externalizantes dizem de um conjunto de reações impulsivas que, exteriorizadas por crianças (ou adolescentes), produzem conflitos e, em padrão repetitivo e persistente, são associados a síndromes psicopatológicas e transtornos. Este artigo tem o objetivo de revisão de literatura sobre o tema, nos três eixos disciplinares da Saúde Coletiva. Segue o método de revisão sistemática, com enfoque empírico e formato narrativo, tomando a ciência como prática social e levantando aspectos qualitativos de literatura produzida entre 2009 e 2019. Os conhecimentos produzidos trazem recortes importantes sobre o tema, porém, o panorama alcançado revela um distanciamento discursivo entre os eixos da epidemiologia e das ciências sociais em saúde, aproximados precariamente no eixo da política, planejamento e gestão em saúde. Os modos de considerar a criança nas pesquisas se dão com o silenciamento infantil, priorizando percepções dos adultos sobre as crianças. Chega-se a considerações sobre a importância de uma efetiva interdisciplinaridade e de uma pedagogia da transdisciplinaridade capaz de transcender o lugar das especialidades e de reconhecer a criança, com a valorização das suas práticas e saberes, como ator central do conhecimento acerca de si mesma.

Abstract The externalizing behaviors refer to a set of impulsive reactions that exteriorized by children (or adolescents) produce conflicts and, in a repetitive and persistent pattern, are associated with psychopathological syndromes and disorders. This article has the objective of empirical review on the subject, in three disciplinary axes of Public Health. It follows the systematic review method, with an empirical focus and narrative format, taking science as social practice and raising qualitative aspects of literature produced between 2009 and 2019. The knowledge produced brings important cuts on the subject, however, the panorama reached reveals a discursive distance between the axes of epidemiology and of the social science, precariously approximated in the axis of health planning. The ways of considering the child in the research are with child silencing, prioritizing adults' perceptions about children. We come to considerations about the importance of effective interdisciplinarity and a pedagogy of transdisciplinarity capable of transcending the place of specialties and of recognizing the child, with the appreciation of his practices and knowledge, as the central actor of knowledge about himself.

BACKGROUND Chagas disease, caused by Trypanosoma cruzi, affects nearly six million people worldwide. Various serological tests have been developed for its diagnosis. OBJECTIVE Examine the performance of a set of commercial immunological assays in relation to the geographical origin of the patient sample comparing four states of Brazil: Amazonas (AM), Mato Grosso do Sul (MS), Minas Gerais (MG) and Piauí (PI). METHODS Seven immunoassays were employed to detect anti-T. cruzi IgG antibodies in 379 patient samples that had been previously diagnosed using the two-step protocol required by the Brazilian Ministry of Health. FINDINGS A significant variation in the percent reactive was calculated for the samples from AM and MS, while the PI and MG showed a significant variation in the percent non-reactive. The average reactivity index was significantly higher for samples from the states of PI and MG states than AM and MS. MAIN CONCLUSIONS All tests presented a satisfactory performance overall. Yet, variations were observed that were associated to the region of origin of the samples. Our analyses suggest that future evaluations of immunoassays should include a sampling of sera from regions where the test will be applied in addition to the available International Biological Reference Standards.

RESUMO O objetivo deste estudo é analisar o perfil clínico-hospitalar de neonatos com o diagnóstico de hérnia diafragmática congênita (HDC), no período de 2008 a 2018 em um hospital de referência materno-infantil. Trata-se de um estudo transversal e analítico descritivo, que incluiu principalmente dados de prontuários com os códigos Q79.0, Q79.1, J986, K44 e K44.0 da Classificação Internacional de Doenças (CID-10). Os critérios de exclusão de prontuários foram o diagnóstico de outros tipos de hérnia diafragmática, sem o aspecto congênito; a internação em unidades que não fossem UTI Neonatal; e a idade no ato de internação igual ou superior a 29 dias. Analisou-se um total de 25.602 prontuários, dos quais 14 corresponderam a HDC. O acometimento por gênero foi de 71,43% masculino (10 casos) e 28,57% feminino (4), com 21,34% das localizações de HDC tipo Bochdalek à direita (3) e 78,57% à esquerda (11). Todos os neonatos deste estudo passaram por ventilação mecânica invasiva (VMI) 9,21 ± 5,55 dias. A cirurgia foi indicada em 11 casos (78,57%), com vias de acesso por toracotomia em 4 (36,36%) e por laparotomia subcostal em 7 (63,64%), todos com uso de dreno torácico homolateral ao hemitórax. O tempo total de internação foi de 19,42 ± 15,36 dias. Observou-se a evolução de alta melhorada em oito pacientes (57,14%) e o óbito de seis (42,86%), com idade de 6,19 ± 4,79 dias, sem referência de acompanhamento do desenvolvimento neuropsicomotor posteriormente. Ocorreram baixas incidências de casos por ano, e o gênero de acometimento, as malformações associadas e o tempo de VMI foram semelhantes a outras populações no mundo.

ABSTRACT The aim of this study is to analyze the clinical and hospital profile of newborns diagnosed with Congenital Diaphragmatic Hernia (CDH) from 2008 to 2018 in a maternal and child reference hospital. It is a cross-sectional and descriptive analytical study, which mainly included data from medical records with the codes Q79.0, Q79.1, J98.6, K44 and K44.0 of the International Classification of Diseases (ICD-10). The exclusion criteria of medical records were the diagnosis of other types of diaphragmatic hernia, without the congenital aspect; hospitalization in units that were not Neonatal ICUs; and the age at admission equal to or greater than 29 days. A total of 25,602 records were analyzed, of which 14 corresponded to CDH. The gender involvement was 71.43% male (10 cases) and 28.57% female (4), with 21.34% of Bochdalek-type CDH located on the right (3) and 78.57% on the left (11). All newborns in this study underwent invasive mechanical ventilation (IMV) 9.21 ± 5.55 days. Surgery was indicated in 11 cases (78.57%), with thoracotomy access routes in four (36.36%) and subcostal laparotomy in seven (63.64%), all using a chest tube homolateral to the hemithorax. The total hospital stay was 19.42 ± 15.36 days. There was an improved discharge evolution in eight patients (57.14%) and the death of six (42.86%), with ages around 6.19 ± 4.79 days, with no follow-up of neuropsychomotor development afterwards. There were low incidences of cases per year, the gender involvement, the associated malformations and the IMV time were similar to other populations in the world.

RESUMEN El objetivo de este estudio es analizar el perfil clínico-hospitalario de neonatos diagnosticados con hernia diafragmática congénita (HDC) en el período de 2008 a 2018 en un hospital de referencia materno-infantil. Este es un estudio transversal, analítico-descriptivo, realizado con base en datos de historias clínicas con los códigos Q79.0, Q79.1, J986, K44 y K44.0 de la Clasificación Internacional de Enfermedades (CIE-10). Los criterios de exclusión de las historias clínicas fueron el diagnóstico de otros tipos de hernia diafragmática sin el aspecto congénito; hospitalización en unidades que no sean UCI neonatales; y edad de ingreso igual o mayor a 29 días. Se analizaron un total de 25.602 registros, de los cuales 14 correspondían a HDC. Entre el género afectado, el 71,43% fue el género masculino (10 casos) y el 28,57% el femenino (4), con un 21,34% de las ubicaciones de la HDC de tipo Bochdalek a la derecha (3) y un 78,57% a la izquierda (11). Todos los recién nacidos en este estudio estuvieron bajo ventilación mecánica invasiva (VMI) por 9,21±5,55 días. La cirugía estuvo indicada para 11 casos (78,57%), con vías de acceso por toracotomía para 4 (36,36%) y laparotomía subcostal para 7 (63,64%), todos con sonda torácica homolateral al hemitórax. La estancia hospitalaria total fue de 19,42±15,36 días. Se observó una mejor evolución del alta en ocho pacientes (57,14%) y muerte de seis (42,86%) con 6,19±4,79 días de edad, sin referencia de seguimiento del desarrollo neuropsicomotor posteriormente. Hubo baja incidencia de casos por año; y el género que acomete, las malformaciones asociadas y el tiempo de VMI fueron similares a otros estudios de la literatura.